Personally quite excited about developments of Foregen & am donating to the cause. Regenerating tissue/organs fully is incredibly exciting. Rosalind - Platform for learning bioinformatics and programming through problem solving. Kindred - Python biomedical relation extraction package that uses a supervised approach (i.e. needs training data). fastq-rs - Can process fastq files at about the speed of the coreutils. nglview - Jupyter widget to interactively view molecular structures and trajectories. ngl - WebGL protein viewer. The Biostar Handbook - Introduces readers to bioinformatics, the scientific discipline at the intersection of biology, computer science, and statistical data analytics dedicated to the digital processing of genomic information. Lattice - Creates design-automation workflows that fundamentally change engineering biology. GuacaMol - Benchmarks for generative chemistry. BioGrakn - Provides an intuitive way to query interconnected and heterogeneous biomedical data in one single place. (Article) Rust-Bio - Provides implementations of many algorithms and data structures that are useful for bioinformatics. Machine Boss - Bioinformatics Open Source Sequence machine. atomium - Python molecular modeller (with .pdb/.cif/.mmtf parsing and production). PoincareMaps - Poincare maps recover continuous hierarchies in single-cell data. OpenMM - Toolkit for molecular simulation using high performance GPU code. BiGG Models - Search the database by model, reaction, metabolite, or gene. (Code) Scanpy - Single-Cell Analysis in Python. elPrep - High-performance tool for preparing .sam/.bam files for variant calling in sequencing pipelines. MultiQC - Searches a given directory for analysis logs and compiles a HTML report. (Code) Diyhplus Wiki - Wiki for open source hardware, do-it-yourself biohacking and practical transhumanism. (Code) Tellurium - Python environment for reproducible dynamical modeling of biological networks. (Web) Chemlambda - Graph rewriting system derived from graphic lambda calculus  which can be seen as a simple model of chemical or biological computing. (Code) FPbase - Fluorescent Protein Database. (HN) CReM - Open-source Python framework to generate chemical structures using a fragment-based approach. Pumas AI - Platform for pharmaceutical modeling and simulation. (HN) PVDH Lab - Stem cell and Developmental neurobiology. ASAP - Automatic Selection And Prediction tools for materials and molecules. Amorphous computing - Refers to computational systems that use very large numbers of identical, parallel processors each having limited computational ability and local interactions. Awesome Single Cell - Community-curated list of software packages and data resources for single-cell, including RNA-seq, ATAC-seq, etc. Cahan Lab - Stem cell engineering, developmental biology, and cancer biology research. Nextflow - Bioinformatics workflow manager that enables the development of portable and reproducible workflows. (Web) (GitHub) MiniFold - Deep Learning for Protein Structure Prediction inspired by DeepMind AlphaFold algorithm. sfaira - Data and model repository for single-cell data. PostEra - Medicinal Chemistry Powered by Machine Learning. Bioregistry - Integrative meta-registry of biological databases, ontologies, and nomenclatures. PyMOL - Molecular visualization system. (Code) Bioinformatics Chat - Podcast about computational biology, bioinformatics, and next generation sequencing. OpenCADD - Python library for structural cheminformatics. Lumol - Classical molecular simulation engine that provides a solid base for developing new algorithms and methods. (Web) MolStar - Comprehensive macromolecular library. (Web) BioGraPy - Biological Graphic tool in Python. FPbase - The Fluorescent Protein Database. (Code) Squidpy - Spatial Molecular Data Analysis in Python. parasail - Pairwise Sequence Alignment Library. CellChat - R toolkit for inference, visualization and analysis of cell-cell communication from single-cell data. scArches - Package to integrate newly produced single-cell datasets into integrated reference atlases. BioModels - Vast repository of mathematical models of biological and biomedical systems. noodles - Bioinformatics I/O libraries in Rust. Datamol - Molecular Manipulation Made Easy. tidysq - Contains tools for analysis and manipulation of biological sequences (including amino acid and nucleic acid – e.g. RNA, DNA – sequences). SeqKit - Cross-platform and ultrafast toolkit for FASTA/Q file manipulation in Go. TaxonKit - Practical and Efficient NCBI Taxonomy Toolkit. unikmer - Toolkit for nucleic acid k-mer analysis, including set operations on k-mers (sketch) optional with TaxIDs but without count information. ProteinSolver - Graph neural network capable of generating novel amino acid sequences that fold into proteins with predetermined topologies. (Docs) Dabble - Membrane protein builder and parameterizer. ffq - Fetch run information from the European Nucleotide Archive (ENA). (Tweet) MolPAL - Molecular Pool-based Active Learning. smof - UNIX-style FASTA tools. ColabFold - Making Protein folding accessible to all via Google Colab. htsget-rs - Bioinformatic file formats accessible to the web. Synthace - Enabling life science, the way it should be done. scispacy - Full spaCy pipeline and models for scientific/biomedical documents. (Web) MoleculeX - New and rapidly growing suite of machine learning methods and software tools for molecule exploration. Biomappings - Community curated and predicted equivalences and related mappings between named biological entities that are not available from primary sources. PheKnowLator - Heterogeneous Biomedical Knowledge Graphs and Benchmarks Constructed Under Alternative Semantic Models. Bandage - Bioinformatics Application for Navigating De novo Assembly Graphs Easily. (Code) Viv - Multiscale visualization of high-resolution multiplexed bioimaging data on the web. PHATE - Visualizing Transitions and Structure for Biological Data Exploration. BioNix - Functional highly reproducible bioinformatics pipelines. SeqFu - General-purpose program to manipulate and parse information from FASTA/FASTQ files, supporting gzipped input files. block aligner - SIMD-accelerated library for computing global and X-drop affine gap sequence alignments using an adaptive block-based algorithm. OpenFold - Trainable & open-source PyTorch reproduction of AlphaFold 2. Arc Institute - New institution for curiosity-driven biomedical science and technology. (Tweet) SeqLike - Unified biological sequence manipulation in Python. ProtTrans - State of the art pre-trained models for proteins.